NHI.no
Annonse
Informasjon

Atopisk eksem, barneeksem, en oversikt

Atopisk eksem er en tilstand med tørr, kløende og betent hud som særlig rammer små barn. Hos babyer består eksemet som regel av små væskende blærer på kinnene og i hodebunnen.

Atopisk eksem (bildet) rammer særlig små barn.

Sist oppdatert:

23. jan. 2023

Dette dokumentet er basert på det profesjonelle dokumentet Atopisk eksem . Referanselisten for dette dokumentet vises nedenfor

  1. Eichenfield LF, Boguniewicz M, Simpson EL, et al. Translating atopic dermatitis management guidelines into practice for primary care providers. Pediatrics. Published online August 3, 2015. doi: 10.1542/peds.2014-3678 DOI
  2. Simons FE; Early Prevention of Asthma in Atopic Children Study Group. H1-antihistamine treatment in young atopic children: effect on urticaria. Ann Allergy Asthma Immunol 2007; 99: 261-6. PubMed
  3. Mohn CH, Blix HS, Halvorsen JA et al. Incidence Trends of Atopic Dermatitis in Infancy and Early Childhood in a Nationwide Prescription Registry Study in Norway. JAMA Netw Open 2018. doi:10.1001/jamanetworkopen.2018.4145 DOI
  4. Howe W, Dellavalle RP, Levy ML et al. Pathogenesis, clinical manifestations, and diagnosis of atopic dermatitis (eczema). UpToDate, last updated Sep 2022. Accessed Jan 2023 www.uptodate.com
  5. Kim J, Kim BE, Leung DYM. Pathophysiology of atopic dermatitis: Clinical implications. Allergy Asthma Proc. 2019;40(2):84-92. PubMed
  6. Hebert AA, Grabell DA. Atopic dermatitis. BestPractice, last reviewed 7 Sept 2020. bestpractice.bmj.com
  7. Spergel JM, Boguniewicz M, Schneider L et al. Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements. Pediatrics 2015; 136: e1530-8. pmid:26598458 PubMed
  8. Eichenfield LF, Tom WL, Chamlin SL, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol 2014; 70:338. PubMed
  9. van den Oord RAHM, Sheikh A. Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: systematic review and meta-analysis. BMJ 2009; 339: b2433. BMJ (DOI)
  10. Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD000133. Cochrane (DOI)
  11. Skjerven HO, Rehbinder EM, Vettukattil R, et al. Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial. Lancet 2020. doi:10.1016/S0140-6736(19)32983-6 DOI
  12. Løvold Berents T, Kurås Skram M. Atopisk eksem. Generell veileder i pediatri, Norsk barnelegeforening. Sist revidert 2018. www.helsebiblioteket.no
  13. Bath-Hextall F, Delamere FM, Williams HC. Dietary exclusions for improving established atopic eczema in adults and children: systematic review. Allergy. 2009 Feb;64(2):258-64. PMID: 19178405 PubMed
  14. Fleischer DM, Bock SA, Spears GC et al. Oral food challenges in children with a diagnosis of food allergy. J Pediatr. 2011 Apr;158(4):578-583.e1. Epub 2010 Oct 28. PMID: 21030035 PubMed
  15. Elyas A. Bradley M. Viktigt att beakta att hudåkommor kan variera beroende på hudtyp. Läkartidningen. 2021,118:20208. lakartidningen.se
  16. Helsedirektoratet (2021). Nasjonal faglig retningslinje for antibiotika i primærhelsetjenesten nettdokument. Oslo: Helsedirektoratet (sist faglig oppdatert 16. november 2021, lest jan 2022).
  17. Berents TL, Saunes M, Schopf T, et al. Atopisk eksem. Tidsskr Den Nor Legeforening. 2018;138(13):1256–9.
  18. Milingou M, Tagka A, Armenaka M, et al. Patch tests in children: a review of 13 years of experience in comparison with previous data. Pediatr Dermatol. 2010 ;27:255-259.
  19. Tollefson MM, Bruckner AL. Atopic dermatitis: Skin directed management. Pediatrics 2014. doi:10.1542/peds.2014-2812 DOI
  20. Chu DK, Chu AWL, Rayner DG, et al. Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. J Allergy Clin Immunol 2023; 152: 1493-1519. pmid:37678572 PubMed
  21. Yin ZQ, Zhang WM, Song GX, et al. Meta-analysis on the comparison between two topical calcineurin inhibitors in atopic dermatitis. J Dermatol. 2012;39:520-526. PubMed
  22. Norsk forening for dermatologi og venereologi. Veiledende anbefalinger for bruk av biologiske legemidler og JAK-hemmere ved atopisk eksem. Versjon 3.0. 15.09.2021. www.legeforeningen.no
  23. Strober B, Mallya UG, Yang M, et al. Treatment Outcomes Associated With Dupilumab Use in Patients With Atopic Dermatitis 1-Year Results From the RELIEVE-AD Study. JAMA Dermatol 2022. PMID: 34910086 PubMed
  24. Silverberg JI, Simpson EL, Wollenberg A, et al. Long-term Efficacy of Baricitinib in Adults With Moderate to Severe Atopic Dermatitis Who Were Treatment Responders or Partial Responders An Extension Study of 2 Randomized Clinical Trials. JAMA Dermatol 2021. pmid:33978711 PubMed
  25. Darsow U, Wollenberg A, Simon D, et al. ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2010;24:317-328. PubMed
  26. Santer M, Muller I, Becque T, et al. Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. BMJ 2022; 379: e072007. doi:10.1136/bmj-2022-072007 DOI
  27. Nankervis H, Thomas KS, Delamere FM, Barbarot S, Rogers NK, Williams HC. Scoping systematic review of treatments for eczema. Southampton (UK): NIHR Journals Library; 2016 May. PMID: 27280278 PubMed
  28. Weidinger S, Novak N. Atopic dermatitis. Lancet. 2016;387(10023):1109-22. PMID: 26377142. PubMed
  29. van Zuuren EJ, Fedorowicz Z, Christensen R, Lavrijsen A, Arents BWM. Emollients and moisturisers for eczema. Cochrane Database of Systematic Reviews 2017, Issue 2. Art. No.: CD012119. pmid: 28166390 PubMed
  30. Ridd MJ, Santer M, MacNeill SJ, et al. Effectiveness and safety of lotion, cream, gel, and ointment emollients for childhood eczema: a pragmatic, randomised, phase 4, superiority trial. Lancet Child Adolesc Health. 2022 May 23:S2352-4642(22)00146-8. Epub ahead of print. PMID: 35617974 PubMed
  31. Santer M, Ridd MJ, Francis NA, et al. Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness. BMJ 2018; 361: k1332. pmid:26525422 PubMed
  32. Cardona ID, Kempe EE, Lary C, Ginder JH, Jain N. Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial. J Allergy Clin Immunol Pract. 2020 Mar;8(3):1014-1021. Epub 2019 Nov 13. PMID: 31733336 PubMed
  33. Matterne U, Böhmer MM, Weisshaar E. Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema. Cochrane Database of Systematic Reviews 2019, Issue 1. Art. No.: CD012167. DOI: 10.1002/14651858.CD012167.pub2. The Cochrane Library
  34. Green C, Colquitt JL, Kirby J, Davidson P. Topical corticosteroids for atopic eczema: clinical and cost effectiveness of once-daily vs. more frequent use. Br J Dermatol 2005; 152: 130-41. PubMed
  35. Cury Martins J, Martins C, Aoki V, et al. Topical tacrolimus for atopic dermatitis. Cochrane Database Syst Rev. 2015 Jul 1;7:CD009864. PMID: 26132597 PubMed
  36. Sigurgeirsson B, Boznanski A, Todd G, et al. Safety and efficacy of pimecrolimus in atopic dermatitis: A 5-year randomized trial. Pediatrics 2015; 135: 597-606. doi:10.1542/peds.2014-1990 DOI
  37. Langeland T. Lokalbehandling av atopisk eksem med kalcineurinhemmere. Tidsskr Nor Lægeforen 2006; 126: 321-2. Tidsskrift for Den norske legeforening
  38. Lam M, Zhu JW, Tadrous M, Drucker AM. Association Between Topical Calcineurin Inhibitor Use and Risk of Cancer, Including Lymphoma, Keratinocyte Carcinoma, and Melanoma: A Systematic Review and Meta-analysis. JAMA Dermatol. 2021 May 1;157(5):549-558. PMID: 33787818 PubMed
  39. Bae JM, Choi YY, Park CO, et al. Efficacy of allergen-specific immunotherapy for atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol 2013 Jul;132(1):110-7. doi: 10.1016/j.jaci.2013.02.044. Epub 2013 May 3.
  40. Yepes-Nunez JJ, Guyatt GH, Gomez-Escobar LG, et al. Allergen Immunotherapy for Atopic Dermatitis: A Systematic Review and Meta-Analysis of Benefits and Harms. J Allergy Clin Immunol. 2022. PMID: 36191689 PubMed
  41. Chang Y-S, Trivedi MK, Jha A, et al. Synbiotics for prevention and treatment of atopic dermatitis: A meta-analysis of randomized clinical trials. JAMA Pediatr 2016. doi: 10.1001/jamapediatrics.2015.3943 DOI
  42. Makrgeorgou A, Leonardi-Bee J, Bath-Hextall FJ et al. Probiotics for treating eczema. Cochrane Database Syst Rev 2018. doi:10.1002/14651858.CD006135.pub3. DOI
  43. George SMC, Karanovic S, Harrison DA, Rani A, Birnie AJ, Bath‐Hextall FJ, Ravenscroft JC, Williams HC. Interventions to reduce Staphylococcus aureus in the management of eczema. Cochrane Database of Systematic Reviews 2019, Issue 10. Art. No.: CD003871. DOI: 10.1002/14651858.CD003871.pub3. Accessed 18 January 2023 The Cochrane Library
  44. Chalmers JR, Haines RH, Bradshaw LE, et al. Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. The Lancet. Published:February 19, 2020.
  45. Greer FR, Sicherer SH, Burks AW; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Allergy and Immunology. Effects of early nutritional interventions on the development of atopic disease in infants and children: The role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics 2008; 121: 183-91. Pediatrics
  46. Hoyt AE, Medico T, Commins SP. Breast Milk and Food Allergy: Connections and Current Recommendations. Pediatr Clin North Am. 2015;62:1493-507. pmid:26456446 PubMed
  47. Boyle RJ, Ierodiakonou D, Khan T, et al. Hydrolysed formula and risk of allergic or autoimmune disease: systematic review and meta-analysis. BMJ 2016; 352: i974. doi:10.1136/bmj.i974 DOI
  48. Yang W, Tu R, Hu Y, et al. Probiotics supplement for the prevention of eczema in children: Study protocol for a meta-analysis and systematic review. Medicine (Baltimore). 2019 Aug;98(34):e16957. PMID: 31441896 PubMed
  49. Lee J, Seto D, Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol 2008; 121: 116-21. PubMed
  50. Mortz CG, Andersen KE, Dellgren C, et al. Atopic dermatitis from adolescence to adulthood in the TOACS cohort: prevalence, persistence and comorbidities. Allergy 2015; 70:836. PubMed
  51. Maintz L, Welchowski T, Herrmann N et al. Machine Learning-Based Deep Phenotyping of Atopic Dermatitis: Severity-Associated Factors in Adolescent and Adult Patients. JAMA Dermatol. 2021 Nov 10:e213668. doi: 10.1001/jamadermatol.2021.3668. Epub ahead of print. PMID: 34757407 PubMed
  52. Thyssen JP, Halling AS, Schmid-Grendelmeier P et al. Comorbidities of atopic dermatitis-what does the evidence say? J Allergy Clin Immunol. 2023 Jan 6:S0091-6749(22)01653-0. Epub ahead of print. PMID: 36621338 PubMed
  53. Craver AE, Chen GF, Cohen JM. Association between Atopic Dermatitis and Hypertension and Hyperlipidemia: A Cross-Sectional Study in the All of Us Research Program. J Am Acad Dermatol 2023. pmid:38008413 PubMed
  54. Sawangjit R, Dilokthornsakul P, Lloyd-Lavery A, Lai NM, Dellavalle R, Chaiyakunapruk N. Systemic treatments for eczema: a network meta‐analysis. Cochrane Database of Systematic Reviews 2020, Issue 9. Art. No.: CD013206. DOI: 10.1002/14651858.CD013206.pub2. DOI
  55. Drucker AM, Morra DE, Prieto-Merino D et al. Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis. JAMA Dermatol. 2022 Mar 16. Epub ahead of print. PMID: 35293977. PubMed
Annonse
Annonse